Netti-Netti
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In the mushroom study there was a control group of 6 subjects. These subjects were given methylphenidate, which is not exactly an inert substance.The premise that mind is a function of the brain falls apart when you consider the well-documented placebo and nocebo effects, which are examples of cognitive processes influencing physiology.
If you want to explore the chemical reactions associated with expectation, you might like this study.
A lot of people would not tolerate such a chemical well. (In one study half the sample experienced disruptive side effects.) Given that there were only 6 subjects in the control group, negative reactions to methylphenidate could easily provide a basis for the conclusion that the observed differences between group differences are due to the controls getting sick!
An an aside, I wonder about the positive effect of psychotherapy on PMS, which has in fact been documented. Also a placebo effect?