That is what makes Science so different from Religion.
What makes science different from religion is that real scientists, as opposed to groupies and scientismists, don't capitalize "science", since science is not a religion a-la Islam, Jain, etc. It's a methodology, not worthy of silly gestures like capitalization. I don't capitalize "socket wrench", even though I find them to be pretty darn useful. Likewise, even though I've got a pretty good list of publications in peer-reviewed journals, I consider science to be bread-and-butter, just a tool. It's not to be capitalized with some kind of daffy para-religious awe.
So, tell me, what is your field, and what are your publications? This is not an unfair question, since that is how scientists "get to know" each other if a face-to-face meeting is not practical. If you're not a scientist, then upon what authority do you presume to tell the world what "Science" as you like to spell it, does and how it does things? Perhaps you have some very good authority, but I tend to be the sort of person who would ask a plumber what plumbing is before I'd ask someone who is a fan of plumbing.
And, to forestall the "you first" response:
1. Lahiri, D. K., and Maloney, B. (2010) The "LEARn" (Latent Early-life Associated Regulation) model integrates environmental risk factors and the developmental basis of Alzheimer's disease, and proposes remedial steps.
Exp. Gerontol. 45, 291-296
2. Maloney, B., Ge, Y. W., Petersen, R. C., Hardy, J., Rogers, J. T., Perez-Tur, J., and Lahiri, D. K. (2010) Functional characterization of three single-nucleotide polymorphisms present in the human APOE promoter sequence: Differential effects in neuronal cells and on DNA-protein interactions.
Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B, 185-201
3. Lahiri, D. K., Maloney, B., Bailey, J., and Ge, Y.-W. (2009) Role of alzheimer's amyloid-beta peptide as a putative transcription factor. In
Peptides: Breaking Away, Proceedings of the Twenty-First American Peptide Symposium (Lebl, M., ed) pp. 185-186, Prompt Scientific Publishing, Bloomington, Indiana, USA
4. Dosunmu, R., Wu, J., Adwan, L., Maloney, B., Basha, M. R., McPherson, C. A., Harry, G. J., Rice, D. C., Zawia, N. H., and Lahiri, D. K. (2009) Lifespan profiles of Alzheimer's disease-associated genes and products in monkeys and mice.
J. Alzheimers Dis. 18, 211-230
5. Lahiri, D. K., Maloney, B., and Zawia, N. H. (2009) The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases.
Mol. Psychiatry 14, 992-1003
6. Lahiri, D. K., Zawia, N. H., Greig, N. H., Sambamurti, K., and Maloney, B. (2008) Early-life events may trigger biochemical pathways for Alzheimer's disease: the "LEARn" model.
Biogerontol.
7. Wen, Y., Yu, W. H., Maloney, B., Bailey, J., Ma, J., Marie, I., Maurin, T., Wang, L., Figueroa, H., Herman, M., Krishnamurthy, P., Liu, L., Planel, E., Lau, L. F., Lahiri, D. K., and Duff, K. (2008) Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing.
Neuron 57, 680-690
8. Wu, J., Basha, M. R., Brock, B., Cox, D. P., Cardozo-Pelaez, F., McPherson, C. A., Harry, J., Rice, D. C., Maloney, B., Chen, D., Lahiri, D. K., and Zawia, N. H. (2008) Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD.
J. Neurosci. 28, 3-9
9. Ge, Y.-W., Maloney, B., Alley, G. M., and Lahiri, D. K. (2007) Important Differences between Human and Mouse APOE Gene Promoters: Implications in Alzheimer’s Disease.
J. Neurochem. 103, 1237-1257
10. Lahiri, D. K., Maloney, B., Basha, M. R., Ge, Y. W., and Zawia, N. H. (2007) How and when environmental agents and dietary factors affect the course of Alzheimer's disease: the "LEARn" model (latent early-life associated regulation) may explain the triggering of AD.
Curr. Alzheimer Res. 4, 219-228
11. Lahiri, D. K., Maloney, B., and Ge, Y.-W. (2006) BACE1 gene promoter is differentially regulated: Detection of a novel promoter region for its cell type–specific regulation.
J. Mol. Neurosci. 28, 193-210
12. Lahiri, D. K., Maloney, B., and Ge, Y.-W. (2006) Functional Domains of the BACE1 and BACE2 promoters and mechanisms of transcriptional suppression of the BACE2 promoter in normal neuronal cells.
J. Mol. Neurosci. 29, 65-80
13. Sokol, D. K., Chen, D., Farlow, M. R., Dunn, D. W., Maloney, B., Zimmer, J. A., and Lahiri, D. K. (2006) High levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggression.
J. Child. Neurol. 21, 444-449
14. Maloney, B., Ge, Y. W., Greig, N. H., and Lahiri, D. K. (2006) Characterization of the human beta-secretase 2 (BACE2) 5'-Flanking region: identification of a 268-bp region as the basal BACE2 promoter.
J. Mol. Neurosci. 29, 81-99
15. Lahiri, D. K., Wavrant De-Vrieze, F., Ge, Y.-W., Maloney, B., and Hardy, J. (2005) Characterization of two APP gene promoter polymorphisms that appear to influence risk of late-onset Alzheimer's disease.
Neurobiol. Aging 26, 1329-1341
16. Lahiri, D. K., Ge, Y.-., W., and Maloney, B. (2005) Characterization of the APP proximal promoter and 5'-untranslated regions: identification of cell-type specific domains and implications in APP gene expression and Alzheimer's disease.
FASEB J. 19, 653-655
17. Du, Y., Chen, X., Wei, X., Bales, K. R., Berg, D. T., Paul, S. M., Farlow, M. R., Maloney, B., Ge, Y.-W., and Lahiri, D. K. (2005) NF-kappaB mediates amyloid beta peptide-stimulated activity of the human apolipoprotein E gene promoter in human astroglial cells.
Brain Res. Mol. Brain Res. 136, 177-188
18. Huang, Z., Elkin, G., Maloney, B. J., Beuhner, N., Arntzen, C. J., Thanavala, Y., and Mason, H. S. (2005) Virus-like particle expression and assembly in plants: hepatitis B and Norwalk viruses.
Vaccine 23, 1851-1858
19. Maloney, B. J., Takeda, N., Suzaki, Y., Ami, Y., Li, T. C., Miyamura, T., Arntzen, C. J., and Mason, H. S. (2005) Challenges in creating a vaccine to prevent hepatitis E.
Vaccine 23, 1870-1874
20. Ge, Y.-W., Ghosh, M., Song, W., Maloney, B., and Lahiri, D. (2004) Mechanism of promoter activity of the beta-amyloid precursor protein gene in different cell types. Identification of a specific 30 bp fragment in the proximal promoter region.
J. Neurochem. 90, 1432-1444
21. Ge, Y.-W., Maloney, B., Sambamurti, K., and Lahiri, D. K. (2004) Functional characterization of the 5' flanking region of the BACE gene: identification of a 91 bp fragment involved in basal level of BACE promoter expression.
FASEB J. 18, 1037-1039
22. Sambamurti, K., Kinsey, R., Maloney, B., Ge, Y. W., and Lahiri, D. K. (2004) Gene structure and organization of the human beta-secretase (BACE) promoter.
FASEB J. 18, 1034-1036
23. Bellingham, S. A., Lahiri, D. K., Maloney, B., La Fontaine, S., Multhaup, G., and Camakaris, J. (2004) Copper depletion down-regulates expression of the Alzheimer's disease amyloid-beta precursor protein gene.
J. Biol. Chem. 279, 20378-20386
24. Maloney, B., Ge, Y. W., Greig, N., and Lahiri, D. K. (2004) Presence of a "CAGA box" in the APP gene unique to amyloid plaque-forming species and absent in all APLP-1/2 genes: implications in Alzheimer's disease.
FASEB J. 18, 1288-1290
25. Guo, P., Scholz, E., Maloney, B., and Welniak, E. (1994) Construction of recombinant avian infectious laryngotracheitis virus expressing the beta-galactosidase gene and DNA sequencing of the insertion region.
Virology 202, 771-781
26. Guo, P., Scholz, E., Turek, J., Nodgreen, R., and Maloney, B. (1993) Assembly pathway of avian infectious laryngotracheitis virus.
Am. J. Vet. Res. 54, 2031-2039