New patterns of observation and behavior is required to move closer to any ultimate truth.
Inasmuch as that's a metanoia, I would agree. Whether a 'new' body of knowledge would be the golden key, as it were, or just another body of knowledge, is something I wonder about.
There's a balance between putting food on the table and being grateful for the food on one's plate. I know bodies of knowledge are necessary for survival, but I think a sense of 'unknowing wonder' is a far better tool for the kind of 'knowing' we're discussing here than a body of knowledge – 'what does it profit a man if he gains the whole world and suffer the loss of his soul?' (cf Mark 8:36).
Knowledge is the veil through which we filter the real, and the risk is we value the knowledge more than the real. I'm reminded of a firework display I was at recently, and as it started, a myriad hands went up holding phones, tablets, etc., as people recorded the event ... so they weren't actually there, they were looking at the event through their devices ... strange.
Nicholas of Cusa, who was very 'quantum-oriented' in his theology, would delight in modern science. 'Entangelent' and 'spooky actions at a distance' are right up his theological ally.
Cusa saw each individual being in relation to all being, and each being is a contraction of the whole, and the whole exists in and as each being in a finite or restricted sense – each individual being is a coalescence of the totality of being into a particular being – he proposed the idea of the cosmos as infinite and without centre, or rather infinite with the centre everywhere.
... and that latter is the proper modern understanding of what religion means when it says man is the centre of the cosmos. Physically, we are located on the third planet orbiting a sun on the edge of a spiral galaxy, among innumerable spiral galaxies, so we are 'out there' when we think of our location in reference to our galaxy, but that's not what we're talking about, and that data is irrelevant to the discussion.
We are the centre in the sense that the infinite coalesces into a finite, a singularity ...
... so rather than, as some might say, we should abandon the theological language of old and embrace, say, Quantum Physics, I'd say there's a much richer dialogue to be had if we embrace Quantum Physics and the theological language of old, because applying the ontological principles of that language, in their living essence rather than the reductive 'dead metaphors' of modernity, then there's whole worlds to be unlocked!